HELIX TOOLS

Plan CRISPR and PCR edits like software.

Design edits, simulate products, and ship lab-ready PDFs from a single console. Built for in-silico-first workflows.

Genome IDE· Helix Tools suite
GPU-awareIn-silico firstWet-lab ready
Helix Tools by OmnisCoder · Bench ready, not just a demo.

Toolbox

Instrument panels for CRISPR, Prime Editing, PCR, and primers.

Core & batch suite

The six originals—planners, PCR, and primer QC—kept exactly where you expect them.

CRISPRPlanner · CRISPR / Prime · Popular

CRISPR / Prime Edit Planner

Paste your target and guides to get distances, RT/PBS helpers, edit physics, and a printable PDF plan validated against published designs.

PCRPCR · Product scan

PCR Product Finder

Scan primer pairs, see GC/Tm and amplicon sizes instantly. Perfect for quick sanity checks and printable reports.

BatchPlanner · Batch multi-edit

Batch Edit Planner

CSV in, multi-edit campaign out. Guide/edit planning at scale for screening runs and multi-target programs.

PCRPCR · Batch scan

PCR Batch Finder

Paste primer pairs once and scan multiple amplicons; export CSV with product counts and flags.

PrimersPrimers · Quality clamp & Tm

Primer Quality Checker

GC%, Tm, clamp heuristics, and dimer checks. Sanity-check single primers or pairs before synthesis or PCR.

BatchPrimers · Batch ordering prep

Batch Primer Checker

Paste a list of primers to get GC, Tm, and flags in one table before you place an order.

CRISPR utilities

Experimental helpers for gRNAs, PAMs, prime editing templates, HDR donors, and reporting.

New
CRISPR utilityCRISPR utility

gRNA Validator

QC guides for GC content, homopolymers, and risky motifs before you order.

CRISPR utilityCRISPR utility

PAM Scanner

Scan sequences for PAM occurrences with surrounding context to pick cut sites fast.

CRISPR utilityCRISPR utility

PegRNA Checker

Validate pegRNA spacer, PBS, and RT lengths plus forbidden motifs before cloning.

CRISPR utilityCRISPR utility

Prime Editing Template Generator

Draft PBS/RT templates for PE2/PE3 with primer-friendly formatting and edit notes.

CRISPR utilityCRISPR utility

ssODN HDR Donor Builder

Build single-stranded donors with blocking mutations, silent tags, and length checks.

CRISPR utilityCRISPR utility

CRISPR Multiplex Planner

Coordinate multi-guide campaigns with spacing checks and per-target metadata.

CRISPR utilityCRISPR utility

PCR Amplicon Designer

Propose amplicons around edits for genotyping or NGS verification reads.

CRISPR utilityCRISPR utility

Silent PAM Destroyer

Introduce silent mutations to remove PAMs without breaking coding sequence.

CRISPR utilityCRISPR utility

Genomic Context Inspector

Summarize exon/intron, GC, and repeat context around a cut to de-risk edits.

CRISPR utilityCRISPR utility

Cas Variant Recommender

Suggest Cas variants by PAM and cut properties when default SpCas9 won’t land.

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CRISPR Report Compiler

Bundle guides, donors, primers, and QC flags into a PDF handoff for the bench.